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Scientists surely have a special responsibility. It is their ideas that form the basis of new technology. They should not be indifferent to the fruits of their ideas. They should forgo experiments that are risky or unethical.
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Advances in technology - hugely beneficial though they are - render us vulnerable in new ways. For instance, our interconnected world depends on elaborate networks: electric power grids, air traffic control, international finance, just-in-time delivery, and so forth.
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It is mistaken to claim that global problems will be solved more quickly if only researchers would abandon their quest to understand the universe and knuckle down to work on an agenda of public or political concerns. These are not 'either/or' options - indeed, there is a positive symbiosis between them.
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The extreme sophistication of modern technology - wonderful though its benefits are - is, ironically, an impediment to engaging young people with basics: with learning how things work.
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The practical case for manned spacef light gets ever-weaker with each advance in robots and miniaturisation - indeed, as a scientist or practical man, I see little purpose in sending people into space at all. But as a human being, I'm an enthusiast for manned missions.
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The 'clean energy' challenge deserves a commitment akin to the Manhattan project or the Apollo moon landing.
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Manufacturing doesn't just mean building cars and metal-bashing; it includes making pharmaceuticals and hi-tech electronics. A crucial part of the process is the research and development that allows better and greener products to come to market. Britain has traditionally had a strong science and engineering base.
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The lives of those such as Charles Darwin and Albert Einstein are plainly of interest in their own right, as well as for the light they shed on the way these great scientists worked. But are 'routine' scientists as fascinating as their science? Here I have my doubts.
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Most practising scientists focus on 'bite-sized' problems that are timely and tractable. The occupational risk is then to lose sight of the big picture.
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As regards my own 'philosophy,' I continue to be inspired by the music, liturgy and architectural tradition of the Anglican Church in which I was brought up. No one can fail to be uplifted by great cathedrals - such as that at Ely, near my home in Cambridge.
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To ensure continuing prosperity in the global economy, nothing is more important than the development and application of knowledge and skills.
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Campaigning against religion can be socially counter-productive. If teachers take the uncompromising line that God and Darwinism are irreconcilable, many young people raised in a faith-based culture will stick with their religion and be lost to science.
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We need to broaden our sympathies both in space and time - and perceive ourselves as part of a long heritage, and stewards for an immense future.
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Issues relating to global health and sustainability must stay high on the agenda if we are to cope with an ageing and ever-increasing population, with growing pressure on resources, and with rising global temperatures. The risks and dangers need to be assessed and then confronted.
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There's now, for the first time, a huge gulf between the artefacts of our everyday life and what even a single expert, let alone the average child, can comprehend. The gadgets that now pervade young people's lives, iPhones and suchlike, are baffling 'black boxes' - pure magic to most people.
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Indeed, the night sky is the part of our environment that's been common to all cultures throughout human history. All have gazed up at the 'vault of heaven' and interpreted it in their own way.
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The U.S., France, Germany and Canada have all responded to the financial crisis by boosting rather than cutting their science funding. The U.K. has not.
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To most people in the U.K., indeed throughout Western Europe, space exploration is primarily perceived as 'what NASA does'. This perception is - in many respects - a valid one. Superpower rivalry during the Cold War ramped up U.S. and Soviet space efforts to a scale that Western Europe had no motive to match.
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I've got no religious beliefs at all.
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We can trace things back to the earlier stages of the Big Bang, but we still don't know what banged and why it banged. That's a challenge for 21st-century science.
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The Blair government perhaps ranks as the best the U.K. has had for 50 years. It cannot match the scale of Attlee's reforms, but has a fine record of constitutional reform and economic competence. In my own areas - science and innovation - there have been well-judged and effective changes.
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The first arrival of earthly life on another celestial body ranks as an epochal event not only for our generation, but in the history of our planet. Neil Armstrong was at the cusp of the Apollo programme. This was a collective technological effort of epic scale, but his is the one name sure to be remembered centuries hence.
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From a personal perspective, I am disappointed that we have yet to really achieve a full understanding of the origins of life on Earth. What was the spark that, billions of years ago, kickstarted the process of evolution that has brought us life as we know it today? I hope that we will get some answers to that in my lifetime.
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If you represent the Earth's lifetime by a single year, say from January when it was made to December, the 21st-century would be a quarter of a second in June - a tiny fraction of the year. But even in this concertinaed cosmic perspective, our century is very, very special: the first when humans can change themselves and their home planet.