Harold E. Varmus Quotes
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I had learned of Gertrude Stein's bon mot that medicine opened all doors. This prompted me, in different moods, to view my future life as literary psychiatrist, globe-trotting tropical disease specialist, or academic internist.
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Every cancer looks different. Every cancer has similarities to other cancers. And we're trying to milk those differences and similarities to do a better job of predicting how things are going to work out and making new drugs.
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Cancer is a collection of many diseases with common principles, and each disease will have to be understood and more effectively controlled on its own terms.
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I believe that we are going to have a much deeper appreciation of what kinds of abnormalities in cancer cells and in the surrounding cells that feed and respond to cancers are vulnerabilities that will allow us to make better predictions of which kinds of drugs will work to treat these cancers.
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Anyone graduating from medical school in 1966 had first to fulfill military service before launching a career. Fiercely opposed to the Vietnam War, I sought to avoid it through an assignment to the Public Health Service.
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I keep encouraging the pharmaceutical companies to put more money into R&D.
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All basic scientists who look to the NCI for funding should know that I will tolerate no retreat on the study of model systems and the pursuit of fundamental biological principles.
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In preparation for a career in academic medicine, I worked as a medical house officer at Columbia-Presbyterian Hospital from 1966 to 1968 and then joined Ira Pastan's laboratory at the National Institutes of Health as a Clinical Associate.
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As an undergraduate at Amherst College, I was devoted to Dickensian novels and antiestablishment journalism while marginally fulfilling premedical requirements.
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Just after graduation in 1966, like many of my contemporaries, I applied for research training at the National Institutes of Health. Perhaps because his wife was a poet, Ira Pastan agreed to take me into his laboratory, despite my lack of scientific credentials.
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Following graduation from Amherst, a Woodrow Wilson Fellowship enabled me to test the depth of my interest in literary scholarship by beginning graduate studies at Harvard University.
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When I read about genetics, I see breakthroughs every day. And while I'm trying to learn more about behavioral science, I must say that I don't feel I get tremendous intellectual stimulation from most of the things I read.
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My ideal summer day was reading on the porch.
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I begin with the premise that behavior is an incredibly important element in medicine. People's habits, their willingness to quit smoking, their willingness to take steps to avoid transmission of HIV, are all behavioral questions.
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In the 1960s and '70s, there wasn't much evidence at all. We knew vaguely the causes of cancer, but methods like genomics were very new.
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Science can improve lives in ways that are elegant in design and moving in practice.
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When high school students ask to spend their afternoons and weekends in my laboratory, I am amazed: I didn't develop that kind of enthusiasm for science until I was 28 years old.
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Our biggest single theme is trying to make the NIH work better with the same amount of money.
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Tobacco, UV rays, viruses, heredity, and age are the main causes of cancer.
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In general, all cancers have been traditionally characterized by the way they appear under the microscope and the organs in which they arise.
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I'm used to being surrounded by really smart 22-year-old students who have no problem saying that something I suggested is not a very good idea.
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The NCI scientific programme leaders meet regularly to ensure that we are not ignoring highly original proposals and that we are not creating an unbalanced grant portfolio.
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Some growths can be detected early, making for increased accuracy in diagnosis. Some can be cured and others controlled.
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A major feature of life at the NIH in late 1960s was the extraordinary offering of evening courses for physicians attempting to become scientists as they neared thirty.