Dominick Edward Blake, PC QC (October 13, 1833 – March 1, 1912), known as Edward Blake, was the second Premier of Ontario, Canada, from 1871 to 1872 and leader of the Liberal Party of Canada from 1880 to 1887. He is one of only three federal permanent Liberal leaders never to become Prime Minister of Canada, the others being Stéphane Dion and the latter's immediate successor Michael Ignatieff. He may be said to have served in the national politics of what developed as the affairs of three nationalities: Canadian, British, and Irish. Blake was also the founder, in 1856, of the Canadian law firm now known as Blake, Cassels & Graydon LLP.