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When you think in terms of public service, I heard so much about what Mother Theresa had done in her life. And I was fortunate enough to get a chance to meet her and talk to her a lot about what motivates her and what drives her. And that, to me, is a person that really is an extraordinary role model.
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It's very, very difficult when you have to prepare for something that might not ever happen.
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When I was a child, there were not that many vaccines. I was vaccinated for polio. I actually got measles as a child. I got pertussis, whooping cough. I remember that very well.
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The most confounding thing of all is that we still haven't identified the cause of 20% to 30% of adult common colds.
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The discovery of HIV in 1983 and the proof that it was the cause of AIDS in 1984 were the first major scientific breakthroughs that provided a specific target for blood-screening tests and opened the doorway to the development of antiretroviral medications.
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A pandemic influenza would mean widespread infection essentially throughout every region of the world.
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The launch of phase 1 Ebola vaccine studies is a first step in developing a vaccine that could be licensed and used in the field to protect not only the front line health care workers but also those living in areas where Ebola virus exists.
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An AIDS-free generation would mean that virtually no child is born with HIV; that, as those children grow up, their risk of becoming infected is far lower than it is today; and that those who become infected can access treatment to help prevent them from developing AIDS and from passing the virus on to others.
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There are a number of candidate vaccines that are in development for HIV/AIDS.
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The worst potential bio-terrorist is nature itself.
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Investigating rare diseases gives researchers more clues about how the healthy immune system functions.
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I consider myself a perpetual student. You seek and learn every day: from an experiment in the lab, from reading a scientific journal, from taking care of a patient. Because of this, I rarely get bored.
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Bioethics is a very, very important field. As we get more and more in the arena of understanding science and getting better opportunities, the fact that you can do things with biological sciences that have an impact on a human being means you must have ethical standards.
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There is an urgent need for a protective Ebola vaccine, and it is important to establish that a vaccine is safe and spurs the immune system to react in a way necessary to protect against infection.
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Is it or is it not ethical to create an embryo, and to create a person for the purpose of getting an organ to give to someone else? Your knee-jerk reaction is 'absolutely not;' but you need the ethical analysis of that to show why and how that is something that you need to stay away from.
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When you vaccinate someone, or when you get infected, the microbe is presenting itself to the immune system in a way that the immune system recognizes the important elements of the microbe and makes an immune response, both an antibody response and a cellular response, to ultimately contain the microbe.
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The difference between H7N9 and H5N1, is that H5N1 kills chickens very rapidly, so it is easy to identify where the infected flocks of chickens are. H7N9 doesn't make the chicken sick, so it has been difficult to pinpoint where the infected chickens are.
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Even the pandemic flu of 1918 only killed one to two percent of the people who were infected.
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The Europeans have lots of data on the use of adjuvanted flu vaccine in the elderly, but I don't think anybody has really good data on adjuvants in children.
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You don't have to vaccinate every man, woman and child in the country if you have a couple of cases of smallpox cropping up.
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Some people feel, you make your case, if they listen to you, fine, if they don't, that's it. That's not what leadership is. Leadership is trying to continue to make a case.
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Better ways to diagnose, treat and prevent E. coli 0157:H7 infections are badly needed.
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Human nature is weak.
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Testing two vaccines against different H1N1s at the same time has never been done.