Authors born in 1949
- Debra Monk Actress, 1949
- Denis Johnson Writer, 1949
- Dennis Green American Football Manager, 1949
- Dennis Lillee Cricketer, 1949
- Dennis Nurkse Poet, 1949
- Dennis Richardson Attorney At Law, 1949
- Don Baylor Baseball Manager, 1949
- Don Johnson Actor, 1949
- Don Scardino Television Director, 1949
- Don Zimmer American Football Player, 1949
- Dorothy Allison Writer, 1949
- Dusty Baker Baseball Manager, 1949
- Dusty Hill Bassist, 1949
- Earl Mac Rauch Novelist, 1949
- Ed Begley, Jr. Actor, 1949
- Ed Dobson Pastor, 1949
- Ed King Musician, 1949
- Eddie Money Musician, 1949
- Edward Hallowell Psychiatrist, 1949
- Edward M. Lerner Author, 1949
- Edwin Soeryadjaya Businessman, 1949
- Efua Dorkenoo Activist, 1949
- Eileen Myles Poet, 1949
- Elana Dykewomon Author, 1949
- Eliot Weinberger Writer, 1949
- Elizabeth Edwards Writer, 1949
- Elizabeth George Author, 1949
- Elizabeth Spelke Psychologist, 1949
- Elizabeth Warren Public Servant, 1949
- Ellen Datlow Editor, 1949
- Ellen Ullman Programmer, 1949
- Emanuel Ax Musician, 1949
- Eric Carmen Singer, 1949
- Eric Taylor Singer-Songwriter, 1949
- Erik Estrada Actor, 1949
- Eva Paterson Founder, 1949
- Francis Rossi Singer-Songwriter, 1949
- Frank Rich Essayist, 1949
- Frankie Faison Actor, 1949
- Franklin Raines Business Executive, 1949