Authors born in 1965
- Rebecca Pidgeon Actress, 1965
- Reggie Lewis Basketball Player, 1965
- Reggie Miller Basketball Player, 1965
- Richard K. Morgan Author, 1965
- Rick Larsen Politician, 1965
- Ricky Dillard Singer, 1965
- Rob Zombie Musician, 1965
- Robert Downey, Jr. Actor, 1965
- Robert Pilatus Model, 1965
- Robin Wilson Musician, 1965
- Roger Jon Ellory Writer, 1965
- Ryan Murphy Writer, 1965
- S. A. Bodeen Author, 1965
- S.G. Browne Author, 1965
- Sadie Frost Actress, 1965
- Salman Khan Film Actor, 1965
- Sam Mendes Theatre Director, 1965
- Sarah Jessica Parker Actress, 1965
- Scott Adsit Actor, 1965
- Scott Brooks Basketball Player, 1965
- Scottie Pippen Basketball Player, 1965
- Sean Patrick Flanery Actor, 1965
- Shah Rukh Khan Actor, 1965
- Shania Twain Singer, 1965
- Shawn Michaels Wrestler, 1965
- Shirley Henderson Actress, 1965
- Simon Fowler Singer, 1965
- Simon Sebag Montefiore Historian, 1965
- Slash Musician, 1965
- Slick Rick Rapper, 1965
- Stephen Gaghan Film Director, 1965
- Steve Coogan Comedian, 1965
- Steve Finley Baseball Player, 1965
- Steve Kerr Basketball Player, 1965
- Steve Scalise Politician, 1965
- Steve Southerland Politician, 1965
- Steve Stivers Politician, 1965
- Steve Waugh Athlete, 1965
- Steve Yzerman Ice Hockey Player, 1965
- Steven Adler Musician, 1965