Authors born in 1980
- Carly Craig Actress, 1980
- Carly Pope Actress, 1980
- Caroline Dries Screenwriter, 1980
- Caron Butler Basketball Player, 1980
- Carrie Keagan Television Personality, 1980
- Casey Wilson Actress, 1980
- CC Sabathia Baseball Player, 1980
- Celeste Ng Writer, 1980
- Channing Tatum Actor, 1980
- Charlamagne Tha God Radio Dj, 1980
- Charles Finch Writer, 1980
- Charles Halford Actor, 1980
- Charlie Hunnam Actor, 1980
- Chelsea Clinton Journalist, 1980
- Chien-Ming Wang Baseball Player, 1980
- Chika Anadu Film Maker, 1980
- Chris Carmack Actor, 1980
- Chris D'Elia Comedian, 1980
- Chris Larson Politician, 1980
- Chris Owen Actor, 1980
- Chris Pine Actor, 1980
- Chrissy Metz Actress, 1980
- Christien Meindertsma Artist, 1980
- Christina Aguilera Singer, 1980
- Christina Ricci Actress, 1980
- Christopher Denham Actor, 1980
- Christopher John Wilson Baseball Player, 1980
- Christopher Masterson Actor, 1980
- Claire Coffee Actress, 1980
- Clarissa Ward Journalist, 1980
- Clay Clark Businessman, 1980
- Conor Oberst Singer-Songwriter, 1980
- Corey Clark Singer, 1980
- Craig Stevens Swimmer, 1980
- Crosby Loggins Singer-Songwriter, 1980
- Cyril Kamar Singer-Songwriter, 1980
- D'Arcy Carden Actress, 1980
- D. J. Cotrona Actor, 1980
- Daisuke Matsuzaka Baseball Player, 1980
- Dallas Michael John Albert Green Musician, 1980