Authors born in 1980
- Rebel Wilson Actress, 1980
- Regina Spektor Singer-Songwriter, 1980
- Remy Ma Rapper, 1980
- Richard Jefferson Basketball Player, 1980
- Richie Castellano Musician, 1980
- Richie Faulkner Musician, 1980
- Ricky Van Veen Businessperson, 1980
- Rishi Sunak Politician, 1980
- Rob Arnold Musician, 1980
- Ryan Gosling Actor, 1980
- Ryan North Writer, 1980
- Sachin H. Jain Physician, 1980
- Sam Heughan Actor, 1980
- Sam Riley Actor, 1980
- Samaire Armstrong Actress, 1980
- Samuel Barnett Actor, 1980
- Sarah Carter Actress, 1980
- Sarah Connor Singer-Songwriter, 1980
- Sarah Drew Actress, 1980
- Sarah Shahi Actress, 1980
- Satoshi Ohno Singer, 1980
- Scott Dixon Racing Automobile Driver, 1980
- Sergio Garcia Golfer, 1980
- Sergio Pizzorno Guitarist, 1980
- Shawn Fanning Businessman, 1980
- Shay Carl Blogger, 1980
- Sibel Kekilli Actress, 1980
- Silvestre Dangond Singer, 1980
- Simon Helberg Actor, 1980
- Slim Thug Rapper, 1980
- Stephen Christian Singer, 1980
- Steve Blake Basketball Player, 1980
- Steven Gerrard Football Player, 1980
- T.I. Actor, 1980
- Tablo Rapper, 1980
- Tamara Feldman Television Actor, 1980
- Tanc Sade Actor, 1980
- Timothy Peter Lambesis Musician, 1980
- Travis Beacham Screenwriter, 1980
- Uday Kiran Actor, 1980