Authors Born on April 22
- Eric Mabius Actor, 1971
- Ethel Smyth Composer, 1858
- Georg Hermes Theologian, 1775
- George Cole Actor, 1925
- Glen Campbell Singer, 1936
- Immanuel Kant Philosopher, 1724
- Issey Miyake Designer, 1938
- J. Robert Oppenheimer Theoretical Physicist, 1904
- Jack Nicholson Film Actor, 1937
- James Langevin Politician, 1964
- James Norman Hall Author, 1887
- Janet Evanovich Writer, 1943
- Jeff Minter Game Designer, 1962
- Jeffrey Dean Morgan Actor, 1966
- John Chilcot Civil Servant, 1939
- John Waters Film Director, 1946
- Josh McDaniels American Football Manager, 1976
- Kaka Football Player, 1982
- Kamla Persad-Bissessar Politician, 1952
- Kenneth Jay Lane Designer, 1932
- Louise Glück Poet, 1943
- Mac Maharaj Politician, 1935
- Machine Gun Kelly Rapper, 1990
- Madame de Stael Writer, 1766
- Marshawn Lynch American Football Player, 1986
- Michelle Ryan Actress, 1984
- Nicholas Herbert Stern Economist, 1946
- Nick Baker Naturalist, 1972
- Nonie Darwish Activist, 1949
- Otto Rank Psychoanalyst, 1884
- Paul Davies Physicist, 1946
- Paula Fox Author, 1923
- Peter Frampton Singer, 1950
- Philip James Bailey Author, 1816
- Randall L. Stephenson Chief Executive Officer, 1960
- Ricardo Izecson dos Santos Leite Soccer Player, 1982
- Rita Levi-Montalcini Neuroscientist, 1909
- Ryan Stiles Actor, 1959
- Sam Altman Entrepreneur, 1985
- Shari Sebbens Actress, 1985