Authors Born on February 21
- A.R. Asher Author, 1998
- Al Sears Saxophonist, 1910
- Alan Chambers Activist, 1972
- Alan Rickman Actor, 1946
- Alan Trammell Baseball Manager, 1958
- Alice Freeman Palmer Educator, 1855
- Allan Williams Businessman, 1930
- Anais Nin Diarist, 1903
- Andres Segovia Classical Guitarist, 1893
- Anne Grant Poet, 1755
- Anthony Daniels Actor, 1946
- Antony Pay Clarinetist, 1945
- Arn Tellem Sports Agent, 1954
- Arvind Ethan David Film Producer, 1975
- Ashley Greene Actress, 1987
- Aunjanue Ellis Actress, 1969
- Barbara Jordan Politician, 1936
- Benjamin Bloom Psychologist, 1913
- Betty Jane Wylie Writer, 1931
- Brander Matthews Writer, 1852
- Braylon Edwards Football Player, 1983
- Brendan Sexton III Actor, 1980
- Bryan Lee O'Malley Cartoonist, 1979
- Carmine Galante Mobster, 1910
- Cathy Richardson Singer-Songwriter, 1969
- Charles Boustany Politician, 1956
- Charlotte Church Singer-Songwriter, 1986
- Chespirito Actor, 1929
- Christine Ebersole Actress, 1953
- Christopher Atkins Actor, 1961
- Chuck Palahniuk Novelist, 1962
- Clemence Dane Writer, 1888
- Corbin Bleu Reivers Actor, 1989
- Cynthia Kenyon Biologist, 1954
- Daniel Ek Chief Technology Officer, 1983
- David Ambrose Novelist, 1943
- David Avidan Poet, 1934
- David Barron Film Producer, 1954
- David Foster Wallace Writer, 1962
- David Frost Political Adviser, 1965