Authors Born on September 22
- Aaron Diehl Pianist, 1985
- Aaron Scharf Historian, 1922
- Alexandra Belyakova Singer, 1990
- Alice Hamilton Scientist, 1869
- Alvin Boyd Kuhn Scientist, 1880
- Andrea Bocelli Singer-Songwriter, 1958
- Andrew Natsios Public Servant, 1949
- Andy Cairns Singer, 1965
- Anna Karina Actress, 1940
- Anne of Austria Queen Consort, 1601
- Ari L. Goldman Journalist, 1949
- Arthur Lowe Actor, 1915
- Arthur Ochs Sulzberger, Jr. Journalist, 1951
- Ashley Eckstein Actor, 1981
- Augustus Baldwin Longstreet Lawyer, 1790
- Babette Deutsch Poet, 1895
- Ben Chifley Politician, 1885
- Bert Murray Football Player, 1942
- Bethany Dillon Music Artist, 1988
- Billie Piper Actress, 1982
- Bob Beauprez Politician, 1948
- Bob Goodlatte Politician, 1952
- Bob Lemon Baseball Manager, 1920
- Bonnie Hunt Actress, 1961
- Brian Keene Author, 1967
- Carrie Fulton Phillips 1873
- Cecil Williams Pastor, 1929
- Charles Brenton Huggins Physician, 1901
- Charles Fessenden Morse Businessman, 1839
- Csanad Szegedi Politician, 1982
- Dan Bucatinsky Actor, 1965
- Daniella Alonso Actress, 1978
- Dannie Abse Poet, 1923
- David Adjaye Architect, 1966
- David Coverdale Singer, 1951
- David Riesman Sociologist, 1909
- David Stern Baseball Manager, 1942
- David Talbot Journalist, 1951
- Denard Robinson American Football Manager, 1990
- Derek Sivers Entrepreneur, 1969