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The mutated Marfan gene creates a defective version of fibrillin, a protein that provides structural support for soft tissues like blood vessels. Marfan victims often die young, in fact, after their aortas grow threadbare and rupture.
Sam Kean
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Guinea pigs are practically synonymous with experiments. Lab rats have become the workhorses of modern medicine. Genetics owes a huge debt to the humble fruit fly. There's almost no branch of the life sciences, in fact, that hasn't leaned heavily on one animal or another.
Sam Kean
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Aluminum is the most common metal in the earth's crust, almost twice as abundant as iron. And one common class of aluminum minerals, collectively called alum, has been in use since at least Greek and Roman times.
Sam Kean
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America was probably Europe's equal scientifically by the end of World War I and certainly surpassed it after the chaos of World War II.
Sam Kean
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X-rays revealed that some people were born without a corpus callosum, and they seemed just fine.
Sam Kean
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We human beings are humane in part because we can look beyond our biology.
Sam Kean
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Except for certain moments - when cells are dividing, for instance - chromosomes don't form compact, countable bodies inside cells. Instead, they unravel and flop about, which makes counting chromosomes a bit like counting strands of ramen in a bowl.
Sam Kean
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The price of diamonds can vary greatly depending on size, cut, color, and other factors, including whether they have a history. But because of the rarity of blue boron diamonds, they often fetch more money than gems of similar quality.
Sam Kean
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Most organisms have loads of junk DNA - less pejoratively, noncoding DNA - cluttering their cells.
Sam Kean
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Among physicists and chemists, cold fusion - nuclear fusion at close to room temperature - enjoys a reputation about on par with creationism.
Sam Kean
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What I find fascinating is the idea that we all have a physical brain, but we also have this mental part, and we have to figure out how they work together.
Sam Kean
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When it comes to the periodic table, the United States really blew its chance to make a name for itself. If you look over a map of all the elements named for cities, states, countries, and continents, it's not surprising that European locales dominate the map.
Sam Kean
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The most profound change that genetics brings about might not be scientific at all. It might be mental and even spiritual enrichment: a more expansive sense of who we humans are, existentially, and where we came from, and how we fit with other life on earth.
Sam Kean
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As a child in the early 1980s, I tended to talk with things in my mouth - food, dentist's tubes, balloons that would fly away, whatever - and if no one else was around, I'd talk anyway.
Sam Kean
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In a vague way, I always knew neurosurgery was different - more delicate, more difficult, more demanding. After all, we say things like, 'I'm no brain surgeon,' for a reason.
Sam Kean
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Before the Human Genome Project, most scientists assumed, based on our complex brains and behaviors, that humans must have around 100,000 genes; some estimates went as high as 150,000.
Sam Kean
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Everywhere in the universe, the periodic table has the same basic structure. Even if an alien civilization's table weren't plotted out in the castle-with-turrets shape we humans favor, their spiral or pyramidal or whatever-shaped periodic table would naturally pause after 118 elements.
Sam Kean
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The hippocampus helps record both types of memories initially, and it helps retain them for the medium term. The hippocampus also helps us access old personal memories in long-term storage in other parts of the brain.
Sam Kean
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The amygdala is one of those brain structures that a lot of people know a little bit about, and there's a definite tendency to conflate the amygdala and the fear response itself - as if the amygdala, and the amygdala alone, 'causes' fear.
Sam Kean
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Things look especially bleak for common killers such as diabetes and heart disease. Those ailments clearly have a genetic component. But when scientists survey genes looking for which mutations patients have in common, they come up empty.
Sam Kean
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On a submicro scale, pure diamond is billions of billions of carbon atoms bonded to one another. If you shrunk yourself down and stood inside the diamond, you'd see nothing but carbon in a perfect pattern in every direction.
Sam Kean
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Mutations can arise anywhere in the genome, in gene DNA and noncoding DNA alike. But mutations to genes have bigger consequences: They can disable proteins and kill a creature.
Sam Kean
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Despite what you might guess, when monitoring your breathing, your body doesn't care whether you're inhaling enough oxygen. It cares only whether you're expelling enough carbon dioxide - that's the gas that sets off the panic button when you're suffocating.
Sam Kean
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Unlike uranium, plutonium was created in an American lab in 1940, but scientists soon realized that it could produce even wilder chain reactions and even bigger explosions. In fact, fearing another country would create it, too, the American government went to great lengths to keep even the existence of plutonium a secret.
Sam Kean
