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I generally disagree with most of the very high margin opportunities. Why? Because it's a business strategy tradeoff: the lower the margin you take, the faster you grow.
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Innovative, bottom-up methods will solve problems that now seem intractable—from energy to poverty to disease. Science and technology, powered by the fuel of entrepreneurial energy, are the largest multipliers of resources we have to solve our many social problems.
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Entrepreneurs have the flexibility and the ability to do things that large companies simply cannot. Could a large company pull off a trick like Amyris, going from anti-malaria medicine to next-generation fuel?
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Climate deniers are clearly the fringe group and need to see a proctologist to find their heads.
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Every big problem is a big opportunity.
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In the next 10 years, data science and software will do more for medicine than all of the biological sciences together.
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We don't need a fuel that's cleaner, we need a fuel that happens to be cleaner, but is half the price of oil.
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There are parts of the country in America, in the Midwest, where wind is a big resource, and we should absolutely use it. But to try and apply it nationally doesn't make sense. There are technologies that will work that are appropriate to certain regions.
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Will biofuel usage require land? Absolutely, but we think the ability to use winter cover crops, degraded land, as well as using sources such as organic waste, sewage, and forest waste means that actual land usage will be limited. Just these sources can replace most of our imported oil by 2030 without touching new land.
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There's no doubt in my mind over the next 25 years how we drive, how we build our houses, how we fly, how we build our buildings, will all change.
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The willingness to fail gives us the freedom to succeed.
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Where most entrepreneurs fail is on the things they don't know they don't know.
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If everyone played it safe, we wouldn't get anywhere.
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It doesn't matter what your probability of failure is. If there's a 90% chance of failure, there's a 10% chance of changing the world.
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I've probably failed more often than anybody else in Silicon Valley. Those don't matter. I don't remember the failures. You remember the big successes.
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Big data will replace the need for 80% of all doctors
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I don’t mind failing, but if I succeed it better be worth succeeding for.
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I do not know what got me interested in technology. What was very clear to me very early on was that I was not interested in religion and that naturally increased my curiosity about science and technology, and I fundamentally believe the two are conflicting.
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I'm not a political person. I'm a techie nerd, and I enjoy the techie part. I mean, all my life, I've loved great technology.
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I believe cellulosic fuels, biofuels made from nonfood crops are the only solution that will make a difference.
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You need a degree of foolishness to cause disruptive change in healthcare. Dare to dream.
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Success comes to those that dare to dream dreams and are foolish enough to try and make them come true.
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One of the best things data can enable us to do is to ask questions we didn't know to ask.
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Not thinking it's possible is a failure of imagination.