Authors Born on April 22
- Aaron Spelling Screenwriter, 1923
- Adrienne Mayor Historian Of Science, 1946
- Alexander Viets Griswold Theologian, 1766
- Amber Heard Actress, 1986
- Andrew Hudgins Poet, 1951
- Arthur Baker Record Producer, 1955
- Arthur Frederick Saunders Officer, 1878
- Aryeh Neier Human Rights Activist, 1937
- Aubrey Menen Writer, 1912
- Bahamadia Rapper, 1966
- Bettie Page Model, 1923
- Blackie Musician, 1987
- Bob Lefsetz Author, 1953
- Byron Allen Comedian, 1961
- Camil Petrescu Novelist, 1894
- Carl J. Lindner, Jr. Businessman, 1919
- Cassidy Freeman Actress, 1982
- Catherine Malandrino Fashion Designer, 1963
- Catherine Mary Stewart Actress, 1959
- Cathy Hughes Entrepreneur, 1947
- Charles Angoff Writer, 1902
- Charles Mingus Bassist, 1922
- Charles S. Swartz Film Maker, 1939
- Charles Shackleford Basketball Player, 1966
- Charlotte Rae Actress, 1926
- Chetan Bhagat Author, 1974
- Colin Tudge Writer, 1943
- Damien Broderick Author, 1944
- Daniel Johns Musician, 1979
- Daniel Lindsay Film Director, 1975
- David J. C. MacKay Physician, 1067
- David Luiz Soccer Player, 1987
- Derek Blasberg Journalist, 1982
- Donald Cram Chemist, 1919
- Donald E. Graham Businessman, 1945
- Donald Tusk Politician, 1957
- Eddie Albert Singer, 1906
- Edith Tiempo Poet, 1919
- Ellen Glasgow Writer, 1873
- Enos Mills Naturalist, 1870