Mischief just seems to follow wherever Dennis appears, but it is the product of good intentions, misdirected helpfulness, good-hearted generosity, and, possibly, an overactive thyroid, ... The Merchant of Dennis The Menace.
From what has been said, it would appear that the possibility of thyroid deficiency should be considered, and if found, should be treated in any woman with a menstrual abnormality or a reproductive problem. It was generally agree that correction of thyroid deficiency solved many such abnormalities and problems - until about 1940.
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